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Collagen Injections
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Collagen Injections
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Collagen injections treat minor imperfections in facial skin, including laughter lines, wrinkles, creases, crow’s feet, and acne scars. Collagen injections are also used to create fuller lips (collagen lip injections)and cheeks, and can be used to treat the chest, neck and back

Length of Surgery

20 minutes – 1 hour


Out patient


Local anesthetic is administered as part of the collagen injection solution

Back to work in...


Back to the gym in...

A couple of days

Treatment Frequency

Multiple treatments may be needed to maintain your desired results


Uneven texture of the skin; allergic reaction; infection; abscess; scarring; skin necrosis ; cold sores

Duration of results

One to six months, though the collagen treatment effects can last two years in some patients.

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Click links below for detail.

Collagen Injection Costs*

Compared to the cost of more invasive cosmetic procedures, collagen injection cost is relatively low. The total collagen injection price will vary depending on the doctor, the number of areas to be treated, the per-injection cost, and where you are having the collagen treatment. The exact price will vary in different regions and from one doctor to another. The American Society of Plastic Surgeons quoted the national average for Collagen Injections is approximately from $397-$490. If you need multiple injections of collagen, the price will be higher. Many patients can expect to pay around $700 or more for a full course of collagen treatment.

Ask the doctor to provide you with a complete collagen treatment price during the initial consultation that covers all aspects of the collagen procedure.

Most cosmetic surgeons and surgical clinics offer flexible collagen injection financing and payment options, some of which allow staggered payments or loans from VARIOUS FINANCING COMPANIES. When comparing collagen injection prices between different cosmetic surgeons, be aware that the cosmetic surgeon's fee does not include the cost of the chin implant itself, nor does it include the surgical facility's cost or the cost of anesthesia. Prescription medication, such as antibiotics and pain medicine are also additional costs to consider.

If you are considering having a collagen treatment but want to explore more about the financing options available before you make your decision, PLEASE CLICK HERE. You can discuss your financial options with your surgeon, and find out if there are any loans of flexi-payment plans that will allow you to achieve the breasts you have always desired.

To find out more about financing options available please click here.

Am I a candidate for Collagen Injection?

Candidates for collagen treatment are typically between 35 and 60, are in good physical and emotional health, and have realistic expectations for the outcome of their particular collagen treatment.

Unsuitable candidates for collagen injections include:

  • Pregnant or nursing women
  • People with allergies to bovine products or lidocaine
  • People with certain medical conditions such as autoimmune diseases
  • People with severe allergies (anaphylaxis) or allergy to injected local anesthetics should not be treated with bovine OR human collagen.


Because injectable bovine collagen is derived from cows it may cause allergic reactions in some patients. Approximately 3% of the population is allergic to bovine collagen; these individuals should not receive this type of collagen treatment. Patients intending to have collagen treatment should opt for human collagen if they have:

  • Allergies to any foods, especially meat products
  • A family or personal history of severe allergies including asthma, hay fever and atopic dermatitis
  • Suffered any previous reaction to a test dose of collagen


Your doctor will evaluate if you are eligible for bovine-derived collagen treatment by carrying out one or two skin tests prior to treatment. No skin test is necessary for human collagen as allergic reactions are not likely to occur.

Your doctor will take a complete medical history in your initial consultation. If you are taking any medications that reduce blood clotting, such as aspirin, anti-inflammatory agents, and some herbal medications, you will be told to stop taking these as they may increase the chance of bleeding

When you have a skin test prior to collagen treatment to determine if you are allergic to bovine collagen, you will have a test dose of bovine collagen injected just below the skin's surface on your forearm.

You must keep an eye on the site for at least 4 weeks for any of the following signs:

  • Redness
  • Swelling
  • Hardness
  • Itching
  • Tenderness


Most reactions will occur within the first three days, but can happen at any time. Report all reactions to your doctor. After the four week observation period (eight weeks if a second test is required) your doctor will advise whether or not you can proceed with bovine collagen treatment.

Before you choose to have a collagen treatment, make sure that you have realistic expectations for what a collagen treatment can do for you, and ensure that you choose an experienced and reputable practitioner.

What are Collagen Injections Procedure?

Collagen injections treat minor imperfections in facial skin, including laughter lines, wrinkles, creases, crow’s feet, and acne scars. Collagen injections are also used to create fuller lips (collagen lip injections) and cheeks, and can be used to treat areas of the chest, back, and neck.

Collagen treatment is a non-surgical procedure that softens lines, wrinkles and furrows on the face. Tiny quantities of collagen are injected under the line or scar through very fine needles, boosting the skin's natural collagen. The effects can be maintained by small ‘top-up’ collagen injections two or three times a year.

Collagen is a natural, essential protein complex that occurs in the human body and is found in skin, muscle, tendons and bones and provides structural support. Collagen molecules form fibrils that produce necessary fibers for our bodies. The configuration of fibers is the foundation for tissue formation and forms a fibrous network on which new cells can grow. Through the natural processes of aging, collagen in the dermis is gradually lost, and it is this that contributes to the formation of facial lines.

Collagen fillers are classified as two types:

  • Collagen fillers containing human collagen much like that found in skin. Human collagen implants are highly purified and isolated from human skin grown in a laboratory
  • Collagen fillers that are bovine-based or mammal-based. Injectable bovine collagen is made of sterile, purified collagen from cow skin
When injected into the body's skin both forms of collagen are accepted as if they were the body's own collagen, forming a network of collagen fibres and “filling out” lines and wrinkles.

A person's own skin may also be used to produce fibroblast cultures or a suspension of collagen. It can also be mixed with synthetic polymethyl-methacrylate (PMMA) beads to form a non-re absorbable injectable implant used for the correction of nasolabial folds, or smile lines.

Collagen injections can be used to improve the skin's contour and fill out depressions in the skin due to lines, wrinkles, scars or injury. During the collagen treatment procedure the doctor will carefully select the injection points and "score" them with a marking pencil. Your doctor may select numerous injection points for each location to be treated. Antiseptic is also applied. Your doctor will then decide on the correct amount of collagen to be used. The collagen filler is injected into the marked points beneath the skin.

There are a number of facial areas that can be treated using collagen, including:
  • Frown (glabellar) lines between the eyebrows
  • Worry lines across the forehead
  • Crow's feet (periorbital lines) at the corner of the eyes
  • Deep smile lines (nasolabial furrows) from side of the nose to corners of the mouth
  • Definition of the lip border (collagen lip treatment)
  • Vertical (perioral) lines on the mouth , usually caused by smoking
  • Lines at the corners of the mouth
  • Acne scars and other soft facial scars
  • Lips - collagen lip injections can add significant volume to the lips or help to re-define the border of the lips

Collagen treatment can be combined with other cosmetic procedures, including botox injections and laser skin resurfacing.

Collagen injections are not permanent. Collagen is a natural protein therefore it eventually breaks down into amino acids that are then absorbed by the body.

Collagen treatment usually lasts anywhere between one and six months, though can last as long as two years. Results may be unpredictable. How long the collagen treatment lasts depends on its location and individual response - muscular activity such as smiling and frowning will reduce its longevity. Repeat treatments are necessary to maintain your desired results. Collagen fillers do not necessarily result in 100 percent improvements, nor are the results permanent.


Collagen Injection Procedure Steps 

Collagen injections are usually performed in the doctor's office by a specially trained nurse or doctor, often without anesthesia, although the collagen filler itself contains lidocaine, which is a local anesthetic. Collagen treatment usually takes between 20 minutes and an hour

These are the usual procedure steps for collagen replacement treatments, though individual practice may vary:

Step 1 – Preparation

  1. The face is washed thoroughly, then the treatment site is wiped with an antiseptic
Step 2 – The injections

The careful selection of injection points is critical to the success of the collagen treatment.
  1. The points of collagen injection are "scored" by the doctor with a marking pencil. Your doctor may select numerous collagen injection points for each location to be treated.
  2. Using a very fine needle, the collagen, local anesthetic and saline are injected just below the skin to fill out the depression. You may experience some minimal discomfort from the needle injection.
  3. Depending on the area treated, massaging may be used to smooth out the collagen before it firms up
Step 3 – The results

Wrinkles, lines and/or scars are significantly improved immediately following the collagen procedure. In some cases, the treated area may initially appear to be overfilled. However, this will soon disperse to produce a more natural-looking appearance. You can go home shortly after the collagen treatment procedure is complete. You will be able to see the final results of your collagen treatment in about a week.


Collagen Injection recovery and healing times

Immediately after the collagen injections, you may experience some swelling and bruising which typically subsides within 48 hours. The treated area may appear red for the first 24 hours and may last up to a week.

It is safe to cover the treated areas with make-up if you wish. Avoid strenuous exercise, sun and drinking alcohol during this time. You may need to return to the doctor’s office in two to three weeks so that the results can be checked and topped up with more collagen if necessary.
You can resume your normal activities immediately; however, you are advised to stay out of the sun. Ensure you use a total sun block if your skin must be unavoidably exposed to the sun.

Sudden, severe pain or any symptoms that are progressive or seem unusual should be reported to the doctor immediately.

Collagen Injection Side Effects and Surgery Risks

Complications are possible with any medical procedure, and complications resulting from collagen fillers are usually minimal.

At the time of collagen treatment most patients report minor discomfort at the injection sites. This is minimized by the addition of lidocaine, a local anesthetic, to the collagen preparation, which numbs the treatment area.

Collagen treatment side effects include:

  1. Swelling
  2. Tenderness
  3. Temporary bruising and discolouration
  4. The collagen is sometimes visible for a while in the form of small white bumps at the treatment site
Collagen treatment risks and complications include:
  1. Uneven texture of the skin
  2. Allergic reaction
  3. Infection
  4. Abscess
  5. Scarring
  6. Skin necrosis - very rarely, if a blood vessel is accidentally blocked by the collagen injection, a small area of skin may die
  7. Cold sores if the collagen lip treatment patient is prone to them
Ensure that you discuss all possible collagen side effects, collagen risks and collagen complications with your doctor who can answer all your questions about complications and their proper treatment during your initial consultation.

Allergic reaction to bovine collagen is usually recognized after the initial skin test(s). In rare cases, allergic reactions may occur during the course of treatment even though there was no reaction to the test dose. They may occur rapidly after collagen treatment or arise weeks to months afterwards. The reaction may clear up in a few days or persist for months. See your doctor immediately if you have an allergic reaction.

Allergic reactions to bovine collagen treatment may include:
  1. Shortness of breath, low blood pressure, and chest pain.
  2. Urticaria (hives)
  3. Red, itchy or sore lumps at injection sites
  4. Scarring when the lumps have resolved
  5. Shorter lasting effect of collagen injections.


Questions to Ask a Surgeon about a collagen treatment procedure

Knowledge is power so arm yourself with the facts before making any decision about collagen treatment; here is an essential check list to help you find the right Perfect Yourself Surgeon.

  1. Am I a good candidate for collagen treatment?
  2. Are my described expectations realistic?
  3. Where is the surgery performed?
  4. How long will the procedure take?
  5. What kind of anesthesia is used?
  6. What is your experience in performing collagen treatment?
  7. Can I see your qualifications?
  8. Ask to see any before and after collagen treatment photographs of recent procedures?
  9. What percentages of your collagen treatment patients have had significant post-surgical complications? (surgeons should disclose this information to you)
  10. How much will my collagen treatment cost?
  11. Do you offer patient financing? (flexible payment schemes for your surgery)
  12. Will you repeat/correct procedures if the agreed goals are not met? If this is the case, will I be charged again?
  13. Ask to observe the exact procedure you are considering before you decided to have surgery if you are unsure (this could be on videotape or in real life).
  14. What is the recovery and healing period for collagen treatment? When can I resume full normal activity?
  15. Have you ever had your malpractice insurance coverage denied, revoked, suspended
  16. Ask for and follow up on patient references (these can be invaluable to finding out what your surgeon is really like and the level of customer satisfaction he/she has received in the past)


Skin Rejuvenation Checklist

Skin Rejuvenation Checklist

Knowledge is power so arm yourself with the facts before making any decision about Collagen Injections procedures; click here for an essential check list to help you find the right Perfect Yourself skin specialist.

Most popular procedures on Perfect Yourself: liposuction, breast augmentation, face lifts, rhinoplasty, tummy tucks
Be sure to also visit our Expert Advice page where you can find great questions from real visitors, Answered by real plastic surgeons, cosmetic dentists, and skin rejuvenation specialists.